This article describes, from a social science perspective, some of the challenges of managing a medical research clinical trial in a post-conflict rural environment. Social science inputs have contributed much to the ongoing global fight against malaria2 and should continue to do so. In this sense, this article describes some of the ethical challenges of clinical research as I faced them in Liberia, revisits the fundamental variance between the ‘two cultures’, that is, of the sciences and the humanities, and suggests the replicability of such research on the condition that it rests on strong interdisciplinary foundations.
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